Nrf2 deficiency causes tooth decolourization due to iron transport disorder in enamel organ
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چکیده
منابع مشابه
Nrf2 deficiency causes tooth decolourization due to iron transport disorder in enamel organ.
Rodents have brownish-yellow incisors whose colour represents their iron content. Iron is deposited into the mature enamel by ameloblasts that outline enamel surface of the teeth. Nrf2 is a basic region-leucine zipper type transcription factor that regulates expression of a range of cytoprotective genes in response to oxidative and xenobiotic stresses. We found that genetically engineered Nrf2-...
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ژورنال
عنوان ژورنال: Genes to Cells
سال: 2004
ISSN: 1356-9597,1365-2443
DOI: 10.1111/j.1356-9597.2004.00753.x